Direct and mediated effects of testosterone: analysis of sex reversed mosaic mice heterozygous for testicular feminization
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چکیده
منابع مشابه
X-inactivation pattern in the epididymis of sex-reversed mice heterozygous for testicular feminization.
Female mice heterozygous for testicular feminization were sex-reversed by means of the autosomal sex reversal mutation {Sxr). Due to X-inactivation, the blastemata for male sex organs in these animals are composed of a mixture of cells, carrying either the wildtype X chromosome or the X chromosome affected with Tfm in an active state. Thus, the two types of cells are sensitive to androgens or i...
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چکیده ندارد.
Studies on testosterone metabolism in subjects with testicular feminization syndrome.
The metabolism of radioactive testosterone simultaneously administered intravenously and either orally or percutaneously has been studied in seven patients with the syndrome of testicular feminization and compared with that of normal males and females. This investigation was carried out in order to determine the relative contribution to urinary 17-oxo and 17beta-hydroxy androstane steroids of l...
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ژورنال
عنوان ژورنال: Cytogenetic and Genome Research
سال: 1998
ISSN: 1424-8581,1424-859X
DOI: 10.1159/000014959